Simple benzopyrans with a fused γ-lactone unit are prepared from an o-disubstituted arene by direct intramolecular alkoxycarbonylation/lactonization promoted by palladium diacetate; the process gives high yields and moderate stereoselectivity, favoring the cis lactone over trans by a factor of 5:1.
|Original language||English (US)|
|Number of pages||4|
|State||Published - Jan 1 1984|
All Science Journal Classification (ASJC) codes
- Drug Discovery
- Organic Chemistry