@article{b01cae80008345dc86462d875f09cc79,
title = "Direct β-alkylation of aldehydes via photoredox organocatalysis",
abstract = "Direct β-alkylation of saturated aldehydes has been accomplished by synergistically combining photoredox catalysis and organocatalysis. Photon-induced enamine oxidation provides an activated β-enaminyl radical intermediate, which readily combines with a wide range of Michael acceptors to produce β-alkyl aldehydes in a highly efficient manner. Furthermore, this redox-neutral, atom-economical C-H functionalization protocol can be achieved both inter-and intramolecularly. Mechanistic studies by various spectroscopic methods suggest that a reductive quenching pathway is operable.",
author = "Terrett, {Jack A.} and Clift, {Michael D.} and MaCmillan, {David W.C.}",
year = "2014",
month = may,
day = "14",
doi = "10.1021/ja502639e",
language = "English (US)",
volume = "136",
pages = "6858--6861",
journal = "Journal of the American Chemical Society",
issn = "0002-7863",
publisher = "American Chemical Society",
number = "19",
}