Developmental analysis of raphe dorsalis unit activity in the rat

Laurence Lanfumey, Barry L. Jacobs

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


Unit activity of raphe dorsalis neurons was recorded in rats between 3 and 24 days of age. Both a regular discharge pattern and a slow firing rate were observed as early as day 3. The frequency of discharge was not statistically different at any age from the mean discharge rate in the adult rat. It was concluded that the electrophysiological activity of 5-HT neurons develops early in the process of maturation, prior to that of the biochemistry and anatomy of these neurons.

Original languageEnglish (US)
Pages (from-to)317-320
Number of pages4
JournalBrain Research
Issue number2
StatePublished - Jun 24 1982

All Science Journal Classification (ASJC) codes

  • Clinical Neurology
  • Molecular Biology
  • General Neuroscience
  • Developmental Biology


  • maturation
  • neonatal rat
  • raphe dorsalis
  • serotonin
  • unit activity


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