Detection of biogenic CO production above vascular cell cultures using a near-room-temperature QC-DFB laser

A. A. Kosterev; F. K. Tittel; W. Durante; M. Allen; R. Köhler; C. Gmachl; F. Capasso; D. L. Sivco; A. Y. Cho

doi:10.1007/s003400100766

Detection of biogenic CO production above vascular cell cultures using a near-room-temperature QC-DFB laser

A. A. Kosterev, F. K. Tittel, W. Durante, M. Allen, R. Köhler, C. Gmachl, F. Capasso, D. L. Sivco, A. Y. Cho

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Abstract

We report the first application of pulsed, near-room-temperature quantum cascade laser technology to the continuous detection of biogenic CO production rates above viable cultures of vascular smooth muscle cells. A computer-controlled sequence of measurements over a 9-h period was obtained, resulting in a minimum detectable CO production of 20 ppb in a 1-m optical path above a standard cell-culture flask. Data-processing procedures for real-time monitoring of both biogenic and ambient atmospheric CO concentrations are described.

Original language	English (US)
Pages (from-to)	95-99
Number of pages	5
Journal	Applied Physics B: Lasers and Optics
Volume	74
Issue number	1
DOIs	https://doi.org/10.1007/s003400100766
State	Published - 2002
Externally published	Yes

All Science Journal Classification (ASJC) codes

General Physics and Astronomy
Physics and Astronomy (miscellaneous)

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10.1007/s003400100766

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abstract = "We report the first application of pulsed, near-room-temperature quantum cascade laser technology to the continuous detection of biogenic CO production rates above viable cultures of vascular smooth muscle cells. A computer-controlled sequence of measurements over a 9-h period was obtained, resulting in a minimum detectable CO production of 20 ppb in a 1-m optical path above a standard cell-culture flask. Data-processing procedures for real-time monitoring of both biogenic and ambient atmospheric CO concentrations are described.",

author = "Kosterev, {A. A.} and Tittel, {F. K.} and W. Durante and M. Allen and R. K{\"o}hler and C. Gmachl and F. Capasso and Sivco, {D. L.} and Cho, {A. Y.}",

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AU - Kosterev, A. A.

AU - Tittel, F. K.

AU - Durante, W.

AU - Allen, M.

AU - Köhler, R.

AU - Gmachl, C.

AU - Capasso, F.

AU - Sivco, D. L.

AU - Cho, A. Y.

PY - 2002

Y1 - 2002

N2 - We report the first application of pulsed, near-room-temperature quantum cascade laser technology to the continuous detection of biogenic CO production rates above viable cultures of vascular smooth muscle cells. A computer-controlled sequence of measurements over a 9-h period was obtained, resulting in a minimum detectable CO production of 20 ppb in a 1-m optical path above a standard cell-culture flask. Data-processing procedures for real-time monitoring of both biogenic and ambient atmospheric CO concentrations are described.

AB - We report the first application of pulsed, near-room-temperature quantum cascade laser technology to the continuous detection of biogenic CO production rates above viable cultures of vascular smooth muscle cells. A computer-controlled sequence of measurements over a 9-h period was obtained, resulting in a minimum detectable CO production of 20 ppb in a 1-m optical path above a standard cell-culture flask. Data-processing procedures for real-time monitoring of both biogenic and ambient atmospheric CO concentrations are described.

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Detection of biogenic CO production above vascular cell cultures using a near-room-temperature QC-DFB laser

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