Detection of biogenic CO production above vascular cell cultures using a near-room-temperature QC-DFB laser

A. A. Kosterev, F. K. Tittel, W. Durante, M. Allen, R. Köhler, C. Gmachl, F. Capasso, D. L. Sivco, A. Y. Cho

Research output: Contribution to journalArticle

32 Scopus citations

Abstract

We report the first application of pulsed, near-room-temperature quantum cascade laser technology to the continuous detection of biogenic CO production rates above viable cultures of vascular smooth muscle cells. A computer-controlled sequence of measurements over a 9-h period was obtained, resulting in a minimum detectable CO production of 20 ppb in a 1-m optical path above a standard cell-culture flask. Data-processing procedures for real-time monitoring of both biogenic and ambient atmospheric CO concentrations are described.

Original languageEnglish (US)
Pages (from-to)95-99
Number of pages5
JournalApplied Physics B: Lasers and Optics
Volume74
Issue number1
DOIs
StatePublished - 2002
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Physics and Astronomy (miscellaneous)
  • Physics and Astronomy(all)

Fingerprint Dive into the research topics of 'Detection of biogenic CO production above vascular cell cultures using a near-room-temperature QC-DFB laser'. Together they form a unique fingerprint.

  • Cite this

    Kosterev, A. A., Tittel, F. K., Durante, W., Allen, M., Köhler, R., Gmachl, C., Capasso, F., Sivco, D. L., & Cho, A. Y. (2002). Detection of biogenic CO production above vascular cell cultures using a near-room-temperature QC-DFB laser. Applied Physics B: Lasers and Optics, 74(1), 95-99. https://doi.org/10.1007/s003400100766