Abstract
Nonlinear independent component analysis is combined with diffusion-map data analysis techniques to detect good observables in high-dimensional dynamic data. These detections are achieved by integrating local principal component analysis of simulation bursts by using eigenvectors of a Markov matrix describing anisotropic diffusion. The widely applicable procedure, a crucial step in model reduction approaches, is illustrated on stochastic chemical reaction network simulations.
Original language | English (US) |
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Pages (from-to) | 16090-16095 |
Number of pages | 6 |
Journal | Proceedings of the National Academy of Sciences of the United States of America |
Volume | 106 |
Issue number | 38 |
DOIs | |
State | Published - Sep 22 2009 |
All Science Journal Classification (ASJC) codes
- General
Keywords
- Chemical reactions
- Dimensionality reduction
- Slow manifold