Abstract
Unusual coordination in the asymmetric allylic alkylation catalyzed by molybdenum (see scheme) was revealed by a study on several ligands, for example, 1. Unexpectedly, only the nitrogen atom of one picolinamide group coordinates to Mo, while the other amide group rigidifies the system. Based on the effectiveness of the bisdeprotonated ligand, the observed reaction can be rationalized and new ligands can be designed for asymmetric induction in allylic alkylations.
Original language | English (US) |
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Pages (from-to) | 1929-1932 |
Number of pages | 4 |
Journal | Angewandte Chemie - International Edition |
Volume | 41 |
Issue number | 11 |
DOIs | |
State | Published - Jun 3 2002 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Catalysis
- Chemistry(all)
Keywords
- Allylic compounds
- Asymmetric catalysis
- Ligand design
- Molybdenum
- Regioselectivity