Dependence of oxygen quenching of intercalated methylene blue triplet lifetime on DNA base‐pair composition

Bruce Berkoff; Mike Hogan; Jane Legrange; Robert Austin

doi:10.1002/bip.360250211

Dependence of oxygen quenching of intercalated methylene blue triplet lifetime on DNA base‐pair composition

Bruce Berkoff, Mike Hogan, Jane Legrange, Robert Austin

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21 Scopus citations

Abstract

We utilize the dynamic quenching of the triplet state of methylene blue by molecular oxygen to observe changes in the rate at which oxygen can penetrate the helix as a function of base‐pair composition. The results indicate that the interior of the oligonucleotide dA‐dT is more accessible than dG‐dC to small molecules such as dioxygen.

Original language	English (US)
Pages (from-to)	307-316
Number of pages	10
Journal	Biopolymers
Volume	25
Issue number	2
DOIs	https://doi.org/10.1002/bip.360250211
State	Published - Feb 1986

All Science Journal Classification (ASJC) codes

Biophysics
Biochemistry
Biomaterials
Organic Chemistry

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title = "Dependence of oxygen quenching of intercalated methylene blue triplet lifetime on DNA base‐pair composition",

abstract = "We utilize the dynamic quenching of the triplet state of methylene blue by molecular oxygen to observe changes in the rate at which oxygen can penetrate the helix as a function of base‐pair composition. The results indicate that the interior of the oligonucleotide dA‐dT is more accessible than dG‐dC to small molecules such as dioxygen.",

author = "Bruce Berkoff and Mike Hogan and Jane Legrange and Robert Austin",

year = "1986",

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doi = "10.1002/bip.360250211",

language = "English (US)",

volume = "25",

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journal = "Biopolymers",

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publisher = "John Wiley and Sons Inc.",

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T1 - Dependence of oxygen quenching of intercalated methylene blue triplet lifetime on DNA base‐pair composition

AU - Berkoff, Bruce

AU - Hogan, Mike

AU - Legrange, Jane

AU - Austin, Robert

PY - 1986/2

Y1 - 1986/2

N2 - We utilize the dynamic quenching of the triplet state of methylene blue by molecular oxygen to observe changes in the rate at which oxygen can penetrate the helix as a function of base‐pair composition. The results indicate that the interior of the oligonucleotide dA‐dT is more accessible than dG‐dC to small molecules such as dioxygen.

AB - We utilize the dynamic quenching of the triplet state of methylene blue by molecular oxygen to observe changes in the rate at which oxygen can penetrate the helix as a function of base‐pair composition. The results indicate that the interior of the oligonucleotide dA‐dT is more accessible than dG‐dC to small molecules such as dioxygen.

UR - https://www.scopus.com/pages/publications/0022666042

UR - https://www.scopus.com/inward/citedby.url?scp=0022666042&partnerID=8YFLogxK

U2 - 10.1002/bip.360250211

DO - 10.1002/bip.360250211

M3 - Article

C2 - 3955193

AN - SCOPUS:0022666042

SN - 0006-3525

VL - 25

SP - 307

EP - 316

JO - Biopolymers

JF - Biopolymers

IS - 2

ER -

Dependence of oxygen quenching of intercalated methylene blue triplet lifetime on DNA base‐pair composition

Abstract

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