Dendritic calcium dynamics

Wade G. Regehr; David W. Tank

doi:10.1016/0959-4388(94)90099-X

Dendritic calcium dynamics

Wade G. Regehr, David W. Tank

Research output: Contribution to journal › Article › peer-review

72 Scopus citations

Abstract

Further characterization of the biochemical components that contribute to calcium handling, together with advances in optical imaging of ion concentration, are providing quantitative information on the dynamics of calcium in the dendrites of neurons in tissue culture, brain slices and in vivo. It has recently been demonstrated that strong spatial gradients and transient calcium elevations result from the geometry and membrane properties of dendrites. These studies are adding to our understanding of calcium's role in synaptic plasticity and in shaping the electrophysiological properties of neurons.

Original language	English (US)
Pages (from-to)	373-382
Number of pages	10
Journal	Current Opinion in Neurobiology
Volume	4
Issue number	3
DOIs	https://doi.org/10.1016/0959-4388(94)90099-X
State	Published - Jun 1994
Externally published	Yes

All Science Journal Classification (ASJC) codes

General Neuroscience

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10.1016/0959-4388(94)90099-X

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title = "Dendritic calcium dynamics",

abstract = "Further characterization of the biochemical components that contribute to calcium handling, together with advances in optical imaging of ion concentration, are providing quantitative information on the dynamics of calcium in the dendrites of neurons in tissue culture, brain slices and in vivo. It has recently been demonstrated that strong spatial gradients and transient calcium elevations result from the geometry and membrane properties of dendrites. These studies are adding to our understanding of calcium's role in synaptic plasticity and in shaping the electrophysiological properties of neurons.",

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year = "1994",

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AB - Further characterization of the biochemical components that contribute to calcium handling, together with advances in optical imaging of ion concentration, are providing quantitative information on the dynamics of calcium in the dendrites of neurons in tissue culture, brain slices and in vivo. It has recently been demonstrated that strong spatial gradients and transient calcium elevations result from the geometry and membrane properties of dendrites. These studies are adding to our understanding of calcium's role in synaptic plasticity and in shaping the electrophysiological properties of neurons.

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Dendritic calcium dynamics

Abstract

All Science Journal Classification (ASJC) codes

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