Demographic methods in epidemiology

Petra Klepac, Jessica C.E. Metcalf

Research output: Chapter in Book/Report/Conference proceedingChapter


Demography is both shaped by and shapes infectious disease dynamics. Infectious pathogens can increase host mortality. Host birth rates introduce new susceptible individuals into the population, which allows infections to persist in the face of the depletion of susceptible individuals that can result from mortality or immunity that can follow infection. Many important processes in infectious disease epidemiology, from transmission to vaccination, vary as a function of age or life stage. Epidemiology thus requires demographic methods. This chapter introduces broad expectations for patterns emerging from the intersection between demography and epidemiology and presents a set of structured population modelling tools that can be used to dissect important processes, including next generation methods, and estimation of R0 in the context of stage structure and with important differences in time-scale between host demography and pathogen life cycle.

Original languageEnglish (US)
Title of host publicationDemographic Methods across the Tree of Life
PublisherOxford University Press
Number of pages11
ISBN (Electronic)9780198838609
StatePublished - Jan 1 2021

All Science Journal Classification (ASJC) codes

  • General Mathematics
  • General Agricultural and Biological Sciences


  • Infection
  • Next generation methods
  • R0
  • Stage structure
  • Time-scale
  • Transmission
  • Vaccination


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