Degradable alkoxide-crosslinked hydrogels

A. Grosse-Sommer, M. In, R. K. Prud'homme

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Degradable acrylate hydrogels have been synthesized by using hydrolytically unstable crosslinkers which break down with prolonged exposure to water. Chelated zirconium alkoxide compounds were used to crosslink poly(N-isopropylacrylamide) gels which degraded within days to weeks as the crosslinkers hydrolyze. Several types of crosslinkers were synthesized by varying the zirconium alkoxide and the number of crosslinking vinyl groups attached to the alkoxide cluster. UV spectroscopy and rheological measurements were used to follow the degradation of these gels.

Original languageEnglish (US)
Pages (from-to)1447-1453
Number of pages7
JournalJournal of Polymer Science, Part A: Polymer Chemistry
Issue number8
StatePublished - Jun 1996

All Science Journal Classification (ASJC) codes

  • Materials Chemistry
  • Polymers and Plastics
  • Organic Chemistry


  • Alkoxide
  • Crosslink
  • Degradable
  • Gels
  • Hydrogels
  • N-isopropylacrylamide
  • Polymerization


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