Degradable alkoxide-crosslinked hydrogels

A. Grosse-Sommer; M. In; R. K. Prud'homme

doi:10.1002/(SICI)1099-0518(199606)34:8<1447::AID-POLA8>3.0.CO;2-X

Degradable alkoxide-crosslinked hydrogels

A. Grosse-Sommer, M. In, R. K. Prud'homme

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Degradable acrylate hydrogels have been synthesized by using hydrolytically unstable crosslinkers which break down with prolonged exposure to water. Chelated zirconium alkoxide compounds were used to crosslink poly(N-isopropylacrylamide) gels which degraded within days to weeks as the crosslinkers hydrolyze. Several types of crosslinkers were synthesized by varying the zirconium alkoxide and the number of crosslinking vinyl groups attached to the alkoxide cluster. UV spectroscopy and rheological measurements were used to follow the degradation of these gels.

Original language	English (US)
Pages (from-to)	1447-1453
Number of pages	7
Journal	Journal of Polymer Science, Part A: Polymer Chemistry
Volume	34
Issue number	8
DOIs	https://doi.org/10.1002/(SICI)1099-0518(199606)34:8<1447::AID-POLA8>3.0.CO;2-X
State	Published - Jun 1996

All Science Journal Classification (ASJC) codes

Materials Chemistry
Polymers and Plastics
Organic Chemistry

Keywords

Alkoxide
Crosslink
Degradable
Gels
Hydrogels
N-isopropylacrylamide
Polymerization

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10.1002/(SICI)1099-0518(199606)34:8<1447::AID-POLA8>3.0.CO;2-X

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title = "Degradable alkoxide-crosslinked hydrogels",

abstract = "Degradable acrylate hydrogels have been synthesized by using hydrolytically unstable crosslinkers which break down with prolonged exposure to water. Chelated zirconium alkoxide compounds were used to crosslink poly(N-isopropylacrylamide) gels which degraded within days to weeks as the crosslinkers hydrolyze. Several types of crosslinkers were synthesized by varying the zirconium alkoxide and the number of crosslinking vinyl groups attached to the alkoxide cluster. UV spectroscopy and rheological measurements were used to follow the degradation of these gels.",

keywords = "Alkoxide, Crosslink, Degradable, Gels, Hydrogels, N-isopropylacrylamide, Polymerization",

author = "A. Grosse-Sommer and M. In and Prud'homme, {R. K.}",

year = "1996",

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T1 - Degradable alkoxide-crosslinked hydrogels

AU - Grosse-Sommer, A.

AU - In, M.

AU - Prud'homme, R. K.

PY - 1996/6

Y1 - 1996/6

N2 - Degradable acrylate hydrogels have been synthesized by using hydrolytically unstable crosslinkers which break down with prolonged exposure to water. Chelated zirconium alkoxide compounds were used to crosslink poly(N-isopropylacrylamide) gels which degraded within days to weeks as the crosslinkers hydrolyze. Several types of crosslinkers were synthesized by varying the zirconium alkoxide and the number of crosslinking vinyl groups attached to the alkoxide cluster. UV spectroscopy and rheological measurements were used to follow the degradation of these gels.

AB - Degradable acrylate hydrogels have been synthesized by using hydrolytically unstable crosslinkers which break down with prolonged exposure to water. Chelated zirconium alkoxide compounds were used to crosslink poly(N-isopropylacrylamide) gels which degraded within days to weeks as the crosslinkers hydrolyze. Several types of crosslinkers were synthesized by varying the zirconium alkoxide and the number of crosslinking vinyl groups attached to the alkoxide cluster. UV spectroscopy and rheological measurements were used to follow the degradation of these gels.

KW - Alkoxide

KW - Crosslink

KW - Degradable

KW - Gels

KW - Hydrogels

KW - N-isopropylacrylamide

KW - Polymerization

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DO - 10.1002/(SICI)1099-0518(199606)34:8<1447::AID-POLA8>3.0.CO;2-X

M3 - Article

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JO - Journal of Polymer Science, Part A: Polymer Chemistry

JF - Journal of Polymer Science, Part A: Polymer Chemistry

IS - 8

ER -

Degradable alkoxide-crosslinked hydrogels

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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