Definition of the boundaries of the origin of DNA replication in simian virus 40

Kiranur N. Subramanian, Thomas Shenk

Research output: Contribution to journalArticle

36 Scopus citations

Abstract

We have determined by use of DNA sequencing techniques the exact location of the deletion in dl 892, a viable deletion mutant of Simian virus 40 (sV40) reported to map very near the unique replication origin or SV40. With the help of this localization we have narrowed down the boundaries of the replication origin to 85 nucleotides within the sequence of SV40.

Original languageEnglish (US)
Pages (from-to)3635-3642
Number of pages8
JournalNucleic acids research
Volume5
Issue number10
DOIs
StatePublished - Oct 1978
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Genetics

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