Decoding cis-regulatory DNAs in the Drosophila genome

Michele Markstein, Michael Levine

Research output: Contribution to journalReview articlepeer-review

57 Scopus citations


Cis-regulatory DNAs control the timing and sites of gene expression during metazoan development. Changes in gene expression are responsible for the morphological diversification of metazoan body plans. However, traditional methods for the identification and characterization of cis-regulatory DNAs are tedious. During the past year, computational methods have been used to identify novel cis-DNAs within the entire Drosophila genome. These methods change the way that cis-DNAs will be analyzed in future studies and offer the promise of unraveling complex gene networks.

Original languageEnglish (US)
Pages (from-to)601-606
Number of pages6
JournalCurrent Opinion in Genetics and Development
Issue number5
StatePublished - Oct 1 2002
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Genetics
  • Developmental Biology


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