Abstract
The pair-rule genes of Drosophila are required for the subdivision of the developing embryo into a repeating series of homologous body segments. One of the pair-rule genes, even-skipped (eve), appears to be particularly important for the overall segmentation pattern since eve- embryos lack all segmental subdivisions in the middle body region. On the basis of homeo box cross-homology we have isolated a gene, S72, which probably corresponds to eve. In embryo tissue sections S72 transcripts show a periodic distribution pattern. The eve- phenotype appears to involve altered patterns of fushi tarazu and engrailed expression. These and other findings suggest that pair-rule gene expression might involve hierarchical cross-regulatory interactions.
Original language | English (US) |
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Pages (from-to) | 961-963 |
Number of pages | 3 |
Journal | Science |
Volume | 233 |
Issue number | 4767 |
State | Published - 1986 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- General