TY - JOUR
T1 - Critical knowledge gaps and research needs related to the environmental dimensions of antibiotic resistance
AU - Larsson, D. G.Joakim
AU - Andremont, Antoine
AU - Bengtsson-Palme, Johan
AU - Brandt, Kristian Koefoed
AU - de Roda Husman, Ana Maria
AU - Fagerstedt, Patriq
AU - Fick, Jerker
AU - Flach, Carl Fredrik
AU - Gaze, William H.
AU - Kuroda, Makoto
AU - Kvint, Kristian
AU - Laxminarayan, Ramanan
AU - Manaia, Celia M.
AU - Nielsen, Kaare Magne
AU - Plant, Laura
AU - Ploy, Marie Cécile
AU - Segovia, Carlos
AU - Simonet, Pascal
AU - Smalla, Kornelia
AU - Snape, Jason
AU - Topp, Edward
AU - van Hengel, Arjon J.
AU - Verner-Jeffreys, David W.
AU - Virta, Marko P.J.
AU - Wellington, Elizabeth M.
AU - Wernersson, Ann Sofie
N1 - Publisher Copyright:
© 2018
PY - 2018/8
Y1 - 2018/8
N2 - There is growing understanding that the environment plays an important role both in the transmission of antibiotic resistant pathogens and in their evolution. Accordingly, researchers and stakeholders world-wide seek to further explore the mechanisms and drivers involved, quantify risks and identify suitable interventions. There is a clear value in establishing research needs and coordinating efforts within and across nations in order to best tackle this global challenge. At an international workshop in late September 2017, scientists from 14 countries with expertise on the environmental dimensions of antibiotic resistance gathered to define critical knowledge gaps. Four key areas were identified where research is urgently needed: 1) the relative contributions of different sources of antibiotics and antibiotic resistant bacteria into the environment; 2) the role of the environment, and particularly anthropogenic inputs, in the evolution of resistance; 3) the overall human and animal health impacts caused by exposure to environmental resistant bacteria; and 4) the efficacy and feasibility of different technological, social, economic and behavioral interventions to mitigate environmental antibiotic resistance.1
AB - There is growing understanding that the environment plays an important role both in the transmission of antibiotic resistant pathogens and in their evolution. Accordingly, researchers and stakeholders world-wide seek to further explore the mechanisms and drivers involved, quantify risks and identify suitable interventions. There is a clear value in establishing research needs and coordinating efforts within and across nations in order to best tackle this global challenge. At an international workshop in late September 2017, scientists from 14 countries with expertise on the environmental dimensions of antibiotic resistance gathered to define critical knowledge gaps. Four key areas were identified where research is urgently needed: 1) the relative contributions of different sources of antibiotics and antibiotic resistant bacteria into the environment; 2) the role of the environment, and particularly anthropogenic inputs, in the evolution of resistance; 3) the overall human and animal health impacts caused by exposure to environmental resistant bacteria; and 4) the efficacy and feasibility of different technological, social, economic and behavioral interventions to mitigate environmental antibiotic resistance.1
KW - Antimicrobial resistance
KW - Environmental pollution
KW - Infectious diseases
KW - Risk assessment
KW - Risk management
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U2 - 10.1016/j.envint.2018.04.041
DO - 10.1016/j.envint.2018.04.041
M3 - Short survey
C2 - 29747082
AN - SCOPUS:85046685863
SN - 0160-4120
VL - 117
SP - 132
EP - 138
JO - Environment international
JF - Environment international
ER -