Cotranslational folding allows misfolding-prone proteins to circumvent deep kinetic traps

Keyphrases

• Misfolding 100%
• Co-translational Folding 100%
• Kinetic Trapping 100%
• Protein Sequence 50%
• Nascent Chain 50%
• Large Proteins 50%
• Native Interaction 50%
• Rare Codon 50%
• Optimal Window Size 50%
• Protein Folding 25%
• Kinetic Model 25%
• Molecular Mechanism 25%
• Protein Domain 25%
• Thermodynamic Stability 25%
• Chain Length 25%
• Fast Folding 25%
• Terminal Residue 25%
• Simulation Algorithm 25%
• All-atom Molecular Dynamics Simulation 25%
• Folding Efficiency 25%
• Folding Kinetics 25%
• Synthesis Rate 25%
• Biomolecular Self-assembly 25%

Biochemistry, Genetics and Molecular Biology

• Codon 100%
• C-Terminus 100%
• Peptide Sequence 100%
• Protein Folding 50%
• Folding Kinetics 50%
• Protein Tertiary Structure 50%
• Molecular Mechanism 50%
• Thermodynamics 50%