Cost, benefit, tonic, phasic: What do response rates tell us about dopamine and motivation?

Research output: Chapter in Book/Report/Conference proceedingConference contribution

87 Scopus citations

Abstract

The role of dopamine in decision making has received much attention from both the experimental and computational communities. However, because reinforcement learning models concentrate on discrete action selection and on phasic dopamine signals, they are silent as to how animals decide upon the rate of their actions, and they fail to account for the prominent effects of dopamine on response rates. We suggest an extension to reinforcement learning models in which response rates are optimally determined by balancing the tradeoff between the cost of fast responding and the benefit of rapid reward acquisition. The resulting behavior conforms well with numerous characteristics of free-operant responding. More importantly, this framework highlights a role for a tonic signal corresponding to the net rate of rewards, in determining the optimal rate of responding. We hypothesize that this critical quantity is conveyed by tonic levels of dopamine, explaining why dopaminergic manipulations exert a global affect on response rates. We further suggest that the effects of motivation on instrumental rates of responding are mediated through its influence on the net reward rate, implying a tight coupling between motivational states and tonic dopamine. The relationships between phasic and tonic dopamine signaling, and between directing and energizing effects of motivation, as well as the implications for motivational control of habitual and goal-directed instrumental action selection, are discussed.

Original languageEnglish (US)
Title of host publicationReward and Decision Making in Corticobasal Ganglia Networks
PublisherBlackwell Publishing Inc.
Pages357-376
Number of pages20
ISBN (Print)1573316741, 9781573316743
DOIs
StatePublished - Jul 2007

Publication series

NameAnnals of the New York Academy of Sciences
Volume1104
ISSN (Print)0077-8923
ISSN (Electronic)1749-6632

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • History and Philosophy of Science

Keywords

  • Cost/benefit
  • Energizing
  • Free operant
  • Generalized drive
  • Motivation
  • Phasic dopamine
  • Reinforcement learning
  • Response rate
  • Tonic dopamine

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  • Cite this

    Niv, Y. (2007). Cost, benefit, tonic, phasic: What do response rates tell us about dopamine and motivation? In Reward and Decision Making in Corticobasal Ganglia Networks (pp. 357-376). (Annals of the New York Academy of Sciences; Vol. 1104). Blackwell Publishing Inc.. https://doi.org/10.1196/annals.1390.018