Correcting for the hemoglobin absorption artifact in fiber photometry data

Run Zhang; Christina K. Kim

doi:10.1016/j.crmeth.2022.100257

Correcting for the hemoglobin absorption artifact in fiber photometry data

Run Zhang, Christina K. Kim

Research output: Contribution to journal › Comment/debate › peer-review

3 Scopus citations

Abstract

Fiber photometry is a widely used fluorescence approach for measuring neuronal activity in freely behaving animals; however, these signals can be contaminated by hemoglobin absorption artifacts. Zhang et al. propose a computational method to quantify and correct hemoglobin photon absorption effects using spectral fiber photometry, resulting in more accurate neuronal activity measurements.

Original language	English (US)
Article number	100257
Journal	Cell Reports Methods
Volume	2
Issue number	7
DOIs	https://doi.org/10.1016/j.crmeth.2022.100257
State	Published - Jul 18 2022
Externally published	Yes

All Science Journal Classification (ASJC) codes

Biotechnology
Biochemistry
Biochemistry, Genetics and Molecular Biology (miscellaneous)
Genetics
Radiology Nuclear Medicine and imaging
Computer Science Applications

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10.1016/j.crmeth.2022.100257

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title = "Correcting for the hemoglobin absorption artifact in fiber photometry data",

abstract = "Fiber photometry is a widely used fluorescence approach for measuring neuronal activity in freely behaving animals; however, these signals can be contaminated by hemoglobin absorption artifacts. Zhang et al. propose a computational method to quantify and correct hemoglobin photon absorption effects using spectral fiber photometry, resulting in more accurate neuronal activity measurements.",

author = "Run Zhang and Kim, {Christina K.}",

note = "Publisher Copyright: {\textcopyright} 2022 The Author(s)",

year = "2022",

month = jul,

day = "18",

doi = "10.1016/j.crmeth.2022.100257",

language = "English (US)",

volume = "2",

journal = "Cell Reports Methods",

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TY - JOUR

T1 - Correcting for the hemoglobin absorption artifact in fiber photometry data

AU - Zhang, Run

AU - Kim, Christina K.

PY - 2022/7/18

Y1 - 2022/7/18

N2 - Fiber photometry is a widely used fluorescence approach for measuring neuronal activity in freely behaving animals; however, these signals can be contaminated by hemoglobin absorption artifacts. Zhang et al. propose a computational method to quantify and correct hemoglobin photon absorption effects using spectral fiber photometry, resulting in more accurate neuronal activity measurements.

AB - Fiber photometry is a widely used fluorescence approach for measuring neuronal activity in freely behaving animals; however, these signals can be contaminated by hemoglobin absorption artifacts. Zhang et al. propose a computational method to quantify and correct hemoglobin photon absorption effects using spectral fiber photometry, resulting in more accurate neuronal activity measurements.

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U2 - 10.1016/j.crmeth.2022.100257

DO - 10.1016/j.crmeth.2022.100257

M3 - Comment/debate

C2 - 35880019

AN - SCOPUS:85134468055

SN - 2667-2375

VL - 2

JO - Cell Reports Methods

JF - Cell Reports Methods

IS - 7

M1 - 100257

ER -

Correcting for the hemoglobin absorption artifact in fiber photometry data

Abstract

All Science Journal Classification (ASJC) codes

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