Core-shell Fe3O4 polydopamine nanoparticles serve multipurpose as drug carrier, catalyst support and carbon adsorbent

Rui Liu, Yunlong Guo, Gloria Odusote, Fengli Qu, Rodney D. Priestley

Research output: Contribution to journalArticle

246 Scopus citations

Abstract

We present the synthesis and multifunctional utilization of core-shell Fe3O4 polydopamine nanoparticles (Fe3O 4@PDA NPs) to serve as the enabling platform for a range of applications including responsive drug delivery, recyclable catalyst support, and adsorbent. Magnetite Fe3O4 NPs formed in a one-pot process by the hydrothermal approach were coated with a polydopamine shell layer of ∼20 nm in thickness. The as prepared Fe3O4@PDA NPs were used for the controlled drug release in a pH-sensitive manner via reversible bonding between catechol and boronic acid groups of PDA and the anticancer drug bortezomib (BTZ), respectively. The facile deposition of Au NPs atop Fe3O4@PDA NPs was achieved by utilizing PDA as both the reducing agent and the coupling agent. The nanocatalysts exhibited high catalytic performance for the reduction of o-nitrophenol. Furthermore, the recovery and reuse of the catalyst was demonstrated 10 times without any detectible loss in activity. Finally, the PDA layers were converted into carbon to obtain Fe3O4@C and used as an adsorbent for the removal of Rhodamine B from an aqueous solution. The synergistic combination of unique features of PDA and magnetic nanoparticles establishes these core-shell NPs as a versatile platform for multiple applications.

Original languageEnglish (US)
Pages (from-to)9167-9171
Number of pages5
JournalACS Applied Materials and Interfaces
Volume5
Issue number18
DOIs
StatePublished - Sep 25 2013

All Science Journal Classification (ASJC) codes

  • Materials Science(all)

Keywords

  • FeO
  • core-shell nanoparticles
  • dopamine
  • multi-functional
  • polydopamine

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