Abstract
The use of DMSO solvent allows control of beta-hydride elimination following alkoxy-palladation of alkenes, producing a side chain trans alkene unit on 2,6-disubstituted tetrahydropyrans. The method is applied towards the synthesis of tetronomycin.
Original language | English (US) |
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Pages (from-to) | 4925-4928 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 30 |
Issue number | 37 |
DOIs | |
State | Published - 1989 |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Drug Discovery
- Organic Chemistry