@article{530e75fe5d4847d9956c1052e0ed0633,
title = "Continuous microfluidic immunomagnetic cell separation",
abstract = "We present a continuous-flow microfluidic device that enables cell by cell separation of cells selectively tagged with magnetic nanoparticles. The cells flow over an array of microfabricated magnetic stripes, which create a series of high magnetic field gradients that trap the magnetically labeled cells and alter their flow direction. The process was observed in real time using a low power microscope. The device has been demonstrated by the separation of leukocytes from whole human blood.",
author = "Inglis, {David W.} and R. Riehn and Austin, {R. H.} and Sturm, {J. C.}",
note = "Funding Information: The authors greatly appreciate the many helpful conversations with B. Frazier, L. R. Huang, C. Prinz, S. Park and W. Ryu, and the previous work of M. Berger and M. Shaw. They also thank N. P. Ong and W. L. Lee for their assistance with the magnetometer. This work was supported by grants from DARPA (MDA972-00-1-0031), NIH (HG01506, E–21–F46–G1), NSF Nanobiology Technology Center (BSCECS9876771), the State of New Jersey (NJCST 99-100-082-2042-007), and the Office of Naval Research (ONR3396044). The authors acknowledge support from the Cornell University National Fabrication Center, where the chemical mechanical polishing and deep silicon etching were performed. Copyright: Copyright 2008 Elsevier B.V., All rights reserved.",
year = "2004",
month = nov,
doi = "10.1063/1.1823015",
language = "English (US)",
volume = "85",
pages = "5093--5095",
journal = "Applied Physics Letters",
issn = "0003-6951",
publisher = "American Institute of Physics",
number = "21",
}