Abstract
One hundred and fifty-one YACs were selected from three libraries with a series of STS and other DNA probes of the human X chromosome p11.2 - p21. 3 region. The YAC contigs, spanning about 35cM in all and generally cover the whole region,were constructed based on the physical analysis of the positive clones. A total of seventy-seven DNA markers of this region were located and ordered on this map with an average 454 kb spacing,in which fifty-three were polymorphic markers with an average 0.6cM genetic spacing. These results facilitate the search for novel genes and the sequence analysis of this region.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 105-106 |
| Number of pages | 2 |
| Journal | Acta Biochimica et Biophysica Sinica |
| Volume | 29 |
| Issue number | 1 |
| State | Published - 1997 |
| Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Molecular Biology
- Biophysics
- Biochemistry
Keywords
- Physical map
- STS
- X chromosome
- YAC contig
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