TY - JOUR
T1 - Constancy of functional residual capacity in the supine position during hypoxia and hyperoxic hypercapnia
AU - Schoene, Robert Blair
AU - Pierson, D. J.
AU - Butler, J.
PY - 1981/1/1
Y1 - 1981/1/1
N2 - Because of the mechanical interrelationship of the respiratory muscles, changes in lung volume may affect the values of mouth occlusion pressures (P(0.1)). Because we wanted to verify the value of P(0.1) in both research and clinical studies, we investigated the effect of hypoxia and hyperoxic hypercapnia of functional residual capacity (FRC) in 6 supine normal male subjects on five separate occasions. The P(0.1) and minute ventillation were highly correlated, and there were no significant changes in FRC at any time. We concluded that P(0.1) can be interpreted as a valid parameter of central respiratory drives in supine subjects during hypoxia and hyperoxic hypercapnia.
AB - Because of the mechanical interrelationship of the respiratory muscles, changes in lung volume may affect the values of mouth occlusion pressures (P(0.1)). Because we wanted to verify the value of P(0.1) in both research and clinical studies, we investigated the effect of hypoxia and hyperoxic hypercapnia of functional residual capacity (FRC) in 6 supine normal male subjects on five separate occasions. The P(0.1) and minute ventillation were highly correlated, and there were no significant changes in FRC at any time. We concluded that P(0.1) can be interpreted as a valid parameter of central respiratory drives in supine subjects during hypoxia and hyperoxic hypercapnia.
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M3 - Article
C2 - 7294513
AN - SCOPUS:0019507061
VL - 124
SP - 508
EP - 510
JO - American Journal of Respiratory and Critical Care Medicine
JF - American Journal of Respiratory and Critical Care Medicine
SN - 1073-449X
IS - 4
ER -