We present an apparatus that noninvasively tracks a moving nanoparticle in three dimensions while providing concurrent sequential spectroscopic measurements. The design, based on confocal microscopy, uses a near-infrared laser and a dark-field condenser for illumination of a gold nanoparticle. By monitoring the scattered light from the nanoparticle and using a piezoelectric stage, the system was able to continuously bring the diffusive particle in a glycerol/water solution back to the focal volume with spatial resolution and response time of less than 210 nm and a millisecond, respectively.
|Original language||English (US)|
|Journal||Applied Physics Letters|
|State||Published - May 29 2006|
All Science Journal Classification (ASJC) codes
- Physics and Astronomy (miscellaneous)