Confocal three dimensional tracking of a single nanoparticle with concurrent spectroscopic readouts

Hu Cang; Chung M. Wong; C. Shan Xu; Abbas H. Rizvi; Haw Yang

doi:10.1063/1.2204652

Confocal three dimensional tracking of a single nanoparticle with concurrent spectroscopic readouts

Hu Cang, Chung M. Wong, C. Shan Xu, Abbas H. Rizvi, Haw Yang

Research output: Contribution to journal › Article › peer-review

115 Scopus citations

Abstract

We present an apparatus that noninvasively tracks a moving nanoparticle in three dimensions while providing concurrent sequential spectroscopic measurements. The design, based on confocal microscopy, uses a near-infrared laser and a dark-field condenser for illumination of a gold nanoparticle. By monitoring the scattered light from the nanoparticle and using a piezoelectric stage, the system was able to continuously bring the diffusive particle in a glycerol/water solution back to the focal volume with spatial resolution and response time of less than 210 nm and a millisecond, respectively.

Original language	English (US)
Article number	223901
Journal	Applied Physics Letters
Volume	88
Issue number	22
DOIs	https://doi.org/10.1063/1.2204652
State	Published - May 29 2006
Externally published	Yes

All Science Journal Classification (ASJC) codes

Physics and Astronomy (miscellaneous)

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10.1063/1.2204652

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title = "Confocal three dimensional tracking of a single nanoparticle with concurrent spectroscopic readouts",

abstract = "We present an apparatus that noninvasively tracks a moving nanoparticle in three dimensions while providing concurrent sequential spectroscopic measurements. The design, based on confocal microscopy, uses a near-infrared laser and a dark-field condenser for illumination of a gold nanoparticle. By monitoring the scattered light from the nanoparticle and using a piezoelectric stage, the system was able to continuously bring the diffusive particle in a glycerol/water solution back to the focal volume with spatial resolution and response time of less than 210 nm and a millisecond, respectively.",

author = "Hu Cang and Wong, {Chung M.} and Xu, {C. Shan} and Rizvi, {Abbas H.} and Haw Yang",

note = "Funding Information: This work was supported by the Office of Science, U.S. Department of Energy under Contract No. DE-AC03-76SF00098, by the University of California at Berkeley, and by the Hellman Family Faculty Fund. H. Chang is acknowledged for assistance in procurement.",

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AU - Cang, Hu

AU - Wong, Chung M.

AU - Xu, C. Shan

AU - Rizvi, Abbas H.

AU - Yang, Haw

N1 - Funding Information: This work was supported by the Office of Science, U.S. Department of Energy under Contract No. DE-AC03-76SF00098, by the University of California at Berkeley, and by the Hellman Family Faculty Fund. H. Chang is acknowledged for assistance in procurement.

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AB - We present an apparatus that noninvasively tracks a moving nanoparticle in three dimensions while providing concurrent sequential spectroscopic measurements. The design, based on confocal microscopy, uses a near-infrared laser and a dark-field condenser for illumination of a gold nanoparticle. By monitoring the scattered light from the nanoparticle and using a piezoelectric stage, the system was able to continuously bring the diffusive particle in a glycerol/water solution back to the focal volume with spatial resolution and response time of less than 210 nm and a millisecond, respectively.

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Confocal three dimensional tracking of a single nanoparticle with concurrent spectroscopic readouts

Abstract

All Science Journal Classification (ASJC) codes

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