Confocal three dimensional tracking of a single nanoparticle with concurrent spectroscopic readouts

Hu Cang, Chung M. Wong, C. Shan Xu, Abbas H. Rizvi, Haw Yang

Research output: Contribution to journalArticle

103 Scopus citations

Abstract

We present an apparatus that noninvasively tracks a moving nanoparticle in three dimensions while providing concurrent sequential spectroscopic measurements. The design, based on confocal microscopy, uses a near-infrared laser and a dark-field condenser for illumination of a gold nanoparticle. By monitoring the scattered light from the nanoparticle and using a piezoelectric stage, the system was able to continuously bring the diffusive particle in a glycerol/water solution back to the focal volume with spatial resolution and response time of less than 210 nm and a millisecond, respectively.

Original languageEnglish (US)
Article number223901
JournalApplied Physics Letters
Volume88
Issue number22
DOIs
StatePublished - May 29 2006
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Physics and Astronomy (miscellaneous)

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