Computational identification of cellular networks and pathways

Florian Markowetz, Olga G. Troyanskaya

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

In this article we highlight recent developments in computational functional genomics to identify networks of functionally related genes and proteins based on diverse sources of genomic data. Our specific focus is on statistical methods to identify genetic networks. We discuss integrated analysis of microarray datasets, methods to combine heterogeneous data sources, the analysis of high-dimensional phenotyping screens and describe efforts to establish a reliable and unbiased gold standard for method comparison and evaluation.

Original languageEnglish (US)
Pages (from-to)478-482
Number of pages5
JournalMolecular BioSystems
Volume3
Issue number7
DOIs
StatePublished - Jan 1 2007

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Molecular Biology

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