TY - JOUR
T1 - Complex movements evoked by microstimulation of precentral cortex
AU - Graziano, Michael S.A.
AU - Taylor, Charlotte S.R.
AU - Moore, Tirin
N1 - Funding Information:
We thank Charles Gross for his invaluable help. This work was supported by NIH grants EY-11347 and MH-12336 and Burroughs Wellcome grant #992817.
PY - 2002/5/30
Y1 - 2002/5/30
N2 - Electrical microstimulation was used to study primary motor and premotor cortex in monkeys. Each stimulation train was 500 ms in duration, approximating the time scale of normal reaching and grasping movements and the time scale of the neuronal activity that normally accompanies movement. This stimulation on a behaviorally relevant time scale evoked coordinated, complex postures that involved many joints. For example, stimulation of one site caused the mouth to open and also caused the hand to shape into a grip posture and move to the mouth. Stimulation of this site always drove the joints toward this final posture, regardless of the direction of movement required to reach the posture. Stimulation of other cortical sites evoked different postures. Postures that involved the arm were arranged across cortex to form a map of hand positions around the body. This stimulation-evoked map encompassed both primary motor and the adjacent premotor cortex. We suggest that these regions fit together into a single map of the workspace around the body.
AB - Electrical microstimulation was used to study primary motor and premotor cortex in monkeys. Each stimulation train was 500 ms in duration, approximating the time scale of normal reaching and grasping movements and the time scale of the neuronal activity that normally accompanies movement. This stimulation on a behaviorally relevant time scale evoked coordinated, complex postures that involved many joints. For example, stimulation of one site caused the mouth to open and also caused the hand to shape into a grip posture and move to the mouth. Stimulation of this site always drove the joints toward this final posture, regardless of the direction of movement required to reach the posture. Stimulation of other cortical sites evoked different postures. Postures that involved the arm were arranged across cortex to form a map of hand positions around the body. This stimulation-evoked map encompassed both primary motor and the adjacent premotor cortex. We suggest that these regions fit together into a single map of the workspace around the body.
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U2 - 10.1016/S0896-6273(02)00698-0
DO - 10.1016/S0896-6273(02)00698-0
M3 - Article
C2 - 12062029
AN - SCOPUS:0037198703
SN - 0896-6273
VL - 34
SP - 841
EP - 851
JO - Neuron
JF - Neuron
IS - 5
ER -