Co-localization of surface-bound molecules and shallow luminescent centers utilizing Forster resonant excitation transfer driven photochemical reactions

Alexei Goun, Herschel Rabitz

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

There is a great promise in utilizing shallow paramagnetic luminescent defects such as NV-centers in conjunction with spin-labeled receptor proteins in biological and chemical sensing. One of the major challenges is the accurate and efficient placement of the receptor protein in the close vicinity of the luminescent center deposited within the host material. We analyze the FRET-driven functionalization of the surface, where the emission of the luminescent center serves as a donor of the excitation, and the photolabile group on the surface as the acceptor. The efficiency of biological detection with a combination of spin-labeled protein receptor and a shallow NV- center is considered.

Original languageEnglish (US)
Title of host publicationQuantum Effects and Measurement Techniques in Biology and Biophotonics
EditorsClarice Aiello, Sergey V. Polyakov, Paige Derr
PublisherSPIE
ISBN (Electronic)9781510669857
DOIs
StatePublished - 2024
EventQuantum Effects and Measurement Techniques in Biology and Biophotonics 2024 - San Francisco, United States
Duration: Jan 27 2024Jan 30 2024

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume12863
ISSN (Print)1605-7422

Conference

ConferenceQuantum Effects and Measurement Techniques in Biology and Biophotonics 2024
Country/TerritoryUnited States
CitySan Francisco
Period1/27/241/30/24

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Keywords

  • FRET
  • NV center
  • biodetection
  • optically detected electron spin resonance
  • photochemistry
  • quantum biology
  • quantum sensing
  • surface functionalization

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