Cis-trans position effect in Salmonella phage P22

R. Kolstad; Lynn William Enquist

doi:10.1007/BF00272213

Cis-trans position effect in Salmonella phage P22

R. Kolstad, Lynn William Enquist

Research output: Contribution to journal › Article › peer-review

Abstract

Two nonsense mutants of Salmonella form a burst size in mixed infection of non-permissive bacteria which lies above that for non-complementing pairs but below that expected for complementation. The two mutants map closely together. To determine whether the two mutants reside in different genes or in the same gene, single bursts following mixed infection of non-permissive bacteria were analyzed for the relative frequency of wild type versus mutant phage. The results indicate that the two mutants lie in two neighboring genes. The mutants exhibit a cis-trans position effect characteristic of structural genes in bacterial operons.

Original language	English (US)
Pages (from-to)	19-25
Number of pages	7
Journal	MGG Molecular & General Genetics
Volume	115
Issue number	1
DOIs	https://doi.org/10.1007/BF00272213
State	Published - Mar 1 1972
Externally published	Yes

All Science Journal Classification (ASJC) codes

Genetics

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10.1007/BF00272213

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title = "Cis-trans position effect in Salmonella phage P22",

abstract = "Two nonsense mutants of Salmonella form a burst size in mixed infection of non-permissive bacteria which lies above that for non-complementing pairs but below that expected for complementation. The two mutants map closely together. To determine whether the two mutants reside in different genes or in the same gene, single bursts following mixed infection of non-permissive bacteria were analyzed for the relative frequency of wild type versus mutant phage. The results indicate that the two mutants lie in two neighboring genes. The mutants exhibit a cis-trans position effect characteristic of structural genes in bacterial operons.",

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AB - Two nonsense mutants of Salmonella form a burst size in mixed infection of non-permissive bacteria which lies above that for non-complementing pairs but below that expected for complementation. The two mutants map closely together. To determine whether the two mutants reside in different genes or in the same gene, single bursts following mixed infection of non-permissive bacteria were analyzed for the relative frequency of wild type versus mutant phage. The results indicate that the two mutants lie in two neighboring genes. The mutants exhibit a cis-trans position effect characteristic of structural genes in bacterial operons.

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Cis-trans position effect in Salmonella phage P22

Abstract

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