It's all under control: The selection between C-C and C-H activation pathways in 8-acylquinolines can be influenced by the choice of catalyst and solvent (see scheme; cod=cycloocta-1,5-diene). In this approach, an unstrained C-C σ bond is activated and subsequent intermolecular carboacylation of an olefin results in the formation of two new C-C σ bonds.
All Science Journal Classification (ASJC) codes
- General Chemistry
- C-C activation
- C-H activation
- Homogeneous catalysis