Chemical strategies for the global analysis of protein function

Benjamin F. Cravatt, Erik J. Sorensen

Research output: Contribution to journalReview articlepeer-review

140 Scopus citations

Abstract

As the human genome project nears completion, biological research is entering a new era in which experimental focus will shift from identifying novel genes to determining the function of gene products. Rising to this challenge, several technologies have emerged that aim to characterise genes and/or proteins collectively rather than individually. Of particular interest is a new breed of strategies that employs synthetic chemistry to enrich our understanding of protein function on a global scale.

Original languageEnglish (US)
Pages (from-to)663-668
Number of pages6
JournalCurrent Opinion in Chemical Biology
Volume4
Issue number6
DOIs
StatePublished - Jan 1 2000
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Biochemistry

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