Abstract
Protein phosphatase 2A is the principal carboxyl methylated protein in cytoplasmic extracts derived from Xenopus eggs arrested in interphase. Levels of methylation approach stoichiometric values after 2 hr of incubation at 22°C. Rates of PP2A methylation increase by over 50% upon addition of cAMP. Methylation is inhibited by okadaic acid at concentrations that inhibit PP2A phosphatase activity.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 372-379 |
| Number of pages | 8 |
| Journal | Biochemical and Biophysical Research Communications |
| Volume | 198 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 15 1994 |
All Science Journal Classification (ASJC) codes
- Molecular Biology
- Biophysics
- Biochemistry
- Cell Biology