Blowing off Steam: Virus Inhibition of cGAS DNA Sensing

Benjamin A. Diner; Ileana M. Cristea

doi:10.1016/j.chom.2015.08.012

Blowing off Steam: Virus Inhibition of cGAS DNA Sensing

Benjamin A. Diner, Ileana M. Cristea

Research output: Contribution to journal › Short survey › peer-review

7 Scopus citations

Abstract

Detection of viral DNA is essential for eliciting mammalian innate immunity. However, viruses have acquired effective mechanisms for blocking host defense. Indeed, in this issue of Cell Host & Microbe, Wu et al. (2015) discover a herpesviral strategy for inhibiting the prominent host sensor of viral DNA, cGAS.

Original language	English (US)
Pages (from-to)	270-272
Number of pages	3
Journal	Cell Host and Microbe
Volume	18
Issue number	3
DOIs	https://doi.org/10.1016/j.chom.2015.08.012
State	Published - Sep 9 2015

All Science Journal Classification (ASJC) codes

Parasitology
Microbiology
Virology

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10.1016/j.chom.2015.08.012

Cite this

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title = "Blowing off Steam: Virus Inhibition of cGAS DNA Sensing",

abstract = "Detection of viral DNA is essential for eliciting mammalian innate immunity. However, viruses have acquired effective mechanisms for blocking host defense. Indeed, in this issue of Cell Host & Microbe, Wu et al. (2015) discover a herpesviral strategy for inhibiting the prominent host sensor of viral DNA, cGAS.",

author = "Diner, {Benjamin A.} and Cristea, {Ileana M.}",

note = "Publisher Copyright: {\textcopyright} 2015 Elsevier Inc.",

year = "2015",

month = sep,

day = "9",

doi = "10.1016/j.chom.2015.08.012",

language = "English (US)",

volume = "18",

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TY - JOUR

T1 - Blowing off Steam

T2 - Virus Inhibition of cGAS DNA Sensing

AU - Diner, Benjamin A.

AU - Cristea, Ileana M.

PY - 2015/9/9

Y1 - 2015/9/9

N2 - Detection of viral DNA is essential for eliciting mammalian innate immunity. However, viruses have acquired effective mechanisms for blocking host defense. Indeed, in this issue of Cell Host & Microbe, Wu et al. (2015) discover a herpesviral strategy for inhibiting the prominent host sensor of viral DNA, cGAS.

AB - Detection of viral DNA is essential for eliciting mammalian innate immunity. However, viruses have acquired effective mechanisms for blocking host defense. Indeed, in this issue of Cell Host & Microbe, Wu et al. (2015) discover a herpesviral strategy for inhibiting the prominent host sensor of viral DNA, cGAS.

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U2 - 10.1016/j.chom.2015.08.012

DO - 10.1016/j.chom.2015.08.012

M3 - Short survey

C2 - 26355212

AN - SCOPUS:84941275224

SN - 1931-3128

VL - 18

SP - 270

EP - 272

JO - Cell Host and Microbe

JF - Cell Host and Microbe

IS - 3

ER -

Blowing off Steam: Virus Inhibition of cGAS DNA Sensing

Abstract

All Science Journal Classification (ASJC) codes

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