Biotechnology at low Reynolds numbers

James P. Brody, Paul Yager, Raymond E. Goldstein, Robert H. Austin

Research output: Contribution to journalArticlepeer-review

432 Scopus citations


The shrinking of liquid handling systems to the micron and submicron size range entails moving into the area of small Reynolds numbers. The fluid dynamics in this regime are very different from the macroscale. We present an intuitive explanation of how the different physics of small Reynolds numbers flow, along with microscopic sizes, can influence device design, and give examples from our own work using fluid flow in microfabricated devices designed for biological processing.

Original languageEnglish (US)
Pages (from-to)3430-3441
Number of pages12
JournalBiophysical Journal
Issue number6
StatePublished - Dec 1996

All Science Journal Classification (ASJC) codes

  • Biophysics


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