Beyond Stereospecificity: Liquids and Mesoscale Organization of Cytoplasm

Anthony A. Hyman; Clifford P. Brangwynne

doi:10.1016/j.devcel.2011.06.013

Beyond Stereospecificity: Liquids and Mesoscale Organization of Cytoplasm

Anthony A. Hyman, Clifford P. Brangwynne

Research output: Contribution to journal › Comment/debate › peer-review

129 Scopus citations

Abstract

The cytoplasm is not a homogenous solution but instead consists of large dynamic assemblies that arise from transient molecular interactions. Some of these structures have been shown to represent liquid droplets of concentrated protein and RNA. Liquid phase separation of cytoplasm may be a fundamental principle of cytoplasmic organization.

Original language	English (US)
Pages (from-to)	14-16
Number of pages	3
Journal	Developmental cell
Volume	21
Issue number	1
DOIs	https://doi.org/10.1016/j.devcel.2011.06.013
State	Published - Jul 19 2011
Externally published	Yes

All Science Journal Classification (ASJC) codes

General Biochemistry, Genetics and Molecular Biology
Molecular Biology
Cell Biology
Developmental Biology

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10.1016/j.devcel.2011.06.013

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title = "Beyond Stereospecificity: Liquids and Mesoscale Organization of Cytoplasm",

abstract = "The cytoplasm is not a homogenous solution but instead consists of large dynamic assemblies that arise from transient molecular interactions. Some of these structures have been shown to represent liquid droplets of concentrated protein and RNA. Liquid phase separation of cytoplasm may be a fundamental principle of cytoplasmic organization.",

author = "Hyman, {Anthony A.} and Brangwynne, {Clifford P.}",

year = "2011",

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AU - Hyman, Anthony A.

AU - Brangwynne, Clifford P.

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N2 - The cytoplasm is not a homogenous solution but instead consists of large dynamic assemblies that arise from transient molecular interactions. Some of these structures have been shown to represent liquid droplets of concentrated protein and RNA. Liquid phase separation of cytoplasm may be a fundamental principle of cytoplasmic organization.

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JO - Developmental cell

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Beyond Stereospecificity: Liquids and Mesoscale Organization of Cytoplasm

Abstract

All Science Journal Classification (ASJC) codes

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