Beyond Stereospecificity: Liquids and Mesoscale Organization of Cytoplasm

Anthony A. Hyman, Clifford P. Brangwynne

Research output: Contribution to journalComment/debatepeer-review

125 Scopus citations


The cytoplasm is not a homogenous solution but instead consists of large dynamic assemblies that arise from transient molecular interactions. Some of these structures have been shown to represent liquid droplets of concentrated protein and RNA. Liquid phase separation of cytoplasm may be a fundamental principle of cytoplasmic organization.

Original languageEnglish (US)
Pages (from-to)14-16
Number of pages3
JournalDevelopmental cell
Issue number1
StatePublished - Jul 19 2011
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Biochemistry, Genetics and Molecular Biology
  • Molecular Biology
  • Cell Biology
  • Developmental Biology


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