Behavioral and physiological correlates of brain serotoninergic unit activity

B. L. Jacobs, J. Heym, M. E. Trulson

Research output: Contribution to journalArticlepeer-review

64 Scopus citations


Raphe unit activity in rats and cats displays a slow and regular discharge pattern across a variety of situations. The activity is, however, state-dependent, displaying a marked reduction during slow wave sleep and almost complete quiescence during REM sleep. Other than the level of synaptic serotonin, very little is known about the physiological variables affecting these neurons. Behaviorally, raphe neuron activity is correlated with arousal or tonic motor activity, and appears to be driven by phasic afferent input. It is hypothesized that these neurons exert a general modulatory role upon physiology and behavior.

Original languageEnglish (US)
Pages (from-to)431-436
Number of pages6
JournalJournal de Physiologie
Issue number2-3
StatePublished - 1981

All Science Journal Classification (ASJC) codes

  • Physiology


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