TY - JOUR
T1 - Bacterially Speaking
AU - Bassler, Bonnie L.
AU - Losick, Richard
N1 - Funding Information:
The authors thank Drs. B. Hammer, W. Chai, A. Hitchcock, C. Waters, and N. Wingreen for critical readings of the manuscript and D. Zusman and L. Kroos for helpful discussions. This work was supported by The Howard Hughes Medical Institute and NIH grants R01 GM 065859 and R01 AI 054442 to B.L.B. and NIH grant R01 GM18568, NSF grant MCB-01 10090, and a Visiting Professorship from the Miller Institute of the University of California at Berkeley to R.L.
PY - 2006/4/21
Y1 - 2006/4/21
N2 - Bacteria use a variety of means to communicate with one another and with their eukaryotic hosts. In some cases, social interactions allow bacteria to synchronize the behavior of all of the members of the group and thereby act like multicellular organisms. By contrast, some bacterial social engagements promote individuality among members within the group and thereby foster diversity. Here we explore the molecular mechanisms underpinning some recently discovered bacterial communication systems. These include long- and short-range chemical signaling channels; one-way, two-way, and multi-way communication; contact-mediated and contact-inhibited signaling; and the use and spread of misinformation or, more dramatically, even deadly information.
AB - Bacteria use a variety of means to communicate with one another and with their eukaryotic hosts. In some cases, social interactions allow bacteria to synchronize the behavior of all of the members of the group and thereby act like multicellular organisms. By contrast, some bacterial social engagements promote individuality among members within the group and thereby foster diversity. Here we explore the molecular mechanisms underpinning some recently discovered bacterial communication systems. These include long- and short-range chemical signaling channels; one-way, two-way, and multi-way communication; contact-mediated and contact-inhibited signaling; and the use and spread of misinformation or, more dramatically, even deadly information.
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U2 - 10.1016/j.cell.2006.04.001
DO - 10.1016/j.cell.2006.04.001
M3 - Review article
C2 - 16630813
AN - SCOPUS:33646032683
SN - 0092-8674
VL - 125
SP - 237
EP - 246
JO - Cell
JF - Cell
IS - 2
ER -