TY - JOUR
T1 - Bacterial social engagements
AU - Henke, Jennifer M.
AU - Bassler, Bonnie L.
N1 - Funding Information:
This work was supported by NIH grants R01 GM 065859 and R01 AI 054442, NSF grant MCB-0343821, and ONR grant N00014–03–1-0183. We thank the members of the Bassler laboratory and Ned Wingreen for critical reading of the manuscript. We apologize to those authors whose work was not cited owing to space restrictions.
PY - 2004/11
Y1 - 2004/11
N2 - Quorum sensing is a process that enables bacteria to communicate using secreted signaling molecules called autoinducers. This process enables a population of bacteria to regulate gene expression collectively and, therefore, control behavior on a community-wide scale. Quorum sensing is widespread in the bacterial world and, generally, processes controlled by quorum sensing are unproductive when undertaken by an individual bacterium but become effective when undertaken by the group. Cell-cell communication can occur within and between bacterial species, and between bacteria and their eukaryotic hosts, which suggests that the chemical lexicon is complex. Prokaryotic and eukaryotic mechanisms for enhancing and inhibiting quorum sensing have been identified, which suggests that manipulation of quorum-sensing-controlled processes could be common in bacterial-bacterial and bacterial-eukaryotic associations.
AB - Quorum sensing is a process that enables bacteria to communicate using secreted signaling molecules called autoinducers. This process enables a population of bacteria to regulate gene expression collectively and, therefore, control behavior on a community-wide scale. Quorum sensing is widespread in the bacterial world and, generally, processes controlled by quorum sensing are unproductive when undertaken by an individual bacterium but become effective when undertaken by the group. Cell-cell communication can occur within and between bacterial species, and between bacteria and their eukaryotic hosts, which suggests that the chemical lexicon is complex. Prokaryotic and eukaryotic mechanisms for enhancing and inhibiting quorum sensing have been identified, which suggests that manipulation of quorum-sensing-controlled processes could be common in bacterial-bacterial and bacterial-eukaryotic associations.
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U2 - 10.1016/j.tcb.2004.09.012
DO - 10.1016/j.tcb.2004.09.012
M3 - Review article
C2 - 15519854
AN - SCOPUS:7444240913
SN - 0962-8924
VL - 14
SP - 648
EP - 656
JO - Trends in Cell Biology
JF - Trends in Cell Biology
IS - 11
ER -