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Asymmetric synthesis of conformationally constrained cis-1-amino-1-phenylcyclohexan-2-ol

  • Chris H. Senanayake
  • , Robert D. Larsen
  • , Lisa M. DiMichele
  • , Ji Liu
  • , Pascal H. Toma
  • , Richard G. Ball
  • , Thomas R. Verhoeven
  • , Paul J. Reider

Research output: Contribution to journalArticlepeer-review

Abstract

A regio- and stereo-controlled synthesis of chiral cis-1-amino-1-phenylcyclohexan-2-ol is described. The optically pure diol 4 was converted to the ligand 8 in 80% yield.

Original languageEnglish (US)
Pages (from-to)1501-1506
Number of pages6
JournalTetrahedron Asymmetry
Volume7
Issue number5
DOIs
StatePublished - May 1996
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

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