Asymmetric synthesis of conformationally constrained cis-1-amino-1-phenylcyclohexan-2-ol

Chris H. Senanayake, Robert D. Larsen, Lisa M. DiMichele, Ji Liu, Pascal H. Toma, Richard G. Ball, Thomas R. Verhoeven, Paul J. Reider

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


A regio- and stereo-controlled synthesis of chiral cis-1-amino-1-phenylcyclohexan-2-ol is described. The optically pure diol 4 was converted to the ligand 8 in 80% yield.

Original languageEnglish (US)
Pages (from-to)1501-1506
Number of pages6
JournalTetrahedron Asymmetry
Issue number5
StatePublished - May 1996
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry


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