Asymmetric synthesis of cis-aminochromanol

Karl B. Hansen, Philippe Rabbat, Shawn A. Springfield, Paul N. Devine, Edward J.J. Grabowski, Paul J. Reider

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

An efficient asymmetric synthesis of cis-aminochromanol was achieved in seven steps. The absolute stereochemistry of cis-aminochromanol was derived from (salen)Co(III)-catalyzed phenol opening of methyl glycidate.

Original languageEnglish (US)
Pages (from-to)8743-8745
Number of pages3
JournalTetrahedron Letters
Volume42
Issue number50
DOIs
StatePublished - Dec 10 2001
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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    Hansen, K. B., Rabbat, P., Springfield, S. A., Devine, P. N., Grabowski, E. J. J., & Reider, P. J. (2001). Asymmetric synthesis of cis-aminochromanol. Tetrahedron Letters, 42(50), 8743-8745. https://doi.org/10.1016/S0040-4039(01)01907-4