Asymmetric reduction of keto oxime ethers using oxazaborolidine reagents. The enantioselective synthesis of cyclic amino alcohols

Richard D. Tillyer; Charles Boudreau; David Tschaen; U. H. Dolling; Paul J. Reider

doi:10.1016/0040-4039(95)00788-E

Asymmetric reduction of keto oxime ethers using oxazaborolidine reagents. The enantioselective synthesis of cyclic amino alcohols

Richard D. Tillyer
, Charles Boudreau
, David Tschaen
, U. H. Dolling
, Paul J. Reider

Research output: Contribution to journal › Article › peer-review

52 Scopus citations

Abstract

Asymmetric reduction of keto oxime ethers 2 catalyzed by oxazaborolidine-borane complex 4 produces the cis amino alcohols 1 efficiently and with high levels of diastereo- and enantioselectivity.

Original language	English (US)
Pages (from-to)	4337-4340
Number of pages	4
Journal	Tetrahedron Letters
Volume	36
Issue number	25
DOIs	https://doi.org/10.1016/0040-4039(95)00788-E
State	Published - Jun 19 1995
Externally published	Yes

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/0040-4039(95)00788-E

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title = "Asymmetric reduction of keto oxime ethers using oxazaborolidine reagents. The enantioselective synthesis of cyclic amino alcohols",

abstract = "Asymmetric reduction of keto oxime ethers 2 catalyzed by oxazaborolidine-borane complex 4 produces the cis amino alcohols 1 efficiently and with high levels of diastereo- and enantioselectivity.",

author = "Tillyer, \{Richard D.\} and Charles Boudreau and David Tschaen and Dolling, \{U. H.\} and Reider, \{Paul J.\}",

year = "1995",

month = jun,

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doi = "10.1016/0040-4039(95)00788-E",

language = "English (US)",

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pages = "4337--4340",

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T1 - Asymmetric reduction of keto oxime ethers using oxazaborolidine reagents. The enantioselective synthesis of cyclic amino alcohols

AU - Tillyer, Richard D.

AU - Boudreau, Charles

AU - Tschaen, David

AU - Dolling, U. H.

AU - Reider, Paul J.

PY - 1995/6/19

Y1 - 1995/6/19

N2 - Asymmetric reduction of keto oxime ethers 2 catalyzed by oxazaborolidine-borane complex 4 produces the cis amino alcohols 1 efficiently and with high levels of diastereo- and enantioselectivity.

AB - Asymmetric reduction of keto oxime ethers 2 catalyzed by oxazaborolidine-borane complex 4 produces the cis amino alcohols 1 efficiently and with high levels of diastereo- and enantioselectivity.

UR - https://www.scopus.com/pages/publications/0029058104

UR - https://www.scopus.com/pages/publications/0029058104#tab=citedBy

U2 - 10.1016/0040-4039(95)00788-E

DO - 10.1016/0040-4039(95)00788-E

M3 - Article

AN - SCOPUS:0029058104

SN - 0040-4039

VL - 36

SP - 4337

EP - 4340

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 25

ER -

Asymmetric reduction of keto oxime ethers using oxazaborolidine reagents. The enantioselective synthesis of cyclic amino alcohols

Abstract

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