Asymmetric reduction of keto oxime ethers using oxazaborolidine reagents. The enantioselective synthesis of cyclic amino alcohols

Richard D. Tillyer, Charles Boudreau, David Tschaen, U. H. Dolling, Paul J. Reider

Research output: Contribution to journalArticle

49 Scopus citations

Abstract

Asymmetric reduction of keto oxime ethers 2 catalyzed by oxazaborolidine-borane complex 4 produces the cis amino alcohols 1 efficiently and with high levels of diastereo- and enantioselectivity.

Original languageEnglish (US)
Pages (from-to)4337-4340
Number of pages4
JournalTetrahedron Letters
Volume36
Issue number25
DOIs
StatePublished - Jun 19 1995
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Asymmetric reduction of keto oxime ethers using oxazaborolidine reagents. The enantioselective synthesis of cyclic amino alcohols'. Together they form a unique fingerprint.

Cite this