Asymmetric reduction of keto oxime ethers using oxazaborolidine reagents. The enantioselective synthesis of cyclic amino alcohols

Richard D. Tillyer; Charles Boudreau; David Tschaen; U. H. Dolling; Paul J. Reider

doi:10.1016/0040-4039(95)00788-E

Asymmetric reduction of keto oxime ethers using oxazaborolidine reagents. The enantioselective synthesis of cyclic amino alcohols

Richard D. Tillyer, Charles Boudreau, David Tschaen, U. H. Dolling, Paul J. Reider

Research output: Contribution to journal › Article › peer-review

51 Scopus citations

Abstract

Asymmetric reduction of keto oxime ethers 2 catalyzed by oxazaborolidine-borane complex 4 produces the cis amino alcohols 1 efficiently and with high levels of diastereo- and enantioselectivity.

Original language	English (US)
Pages (from-to)	4337-4340
Number of pages	4
Journal	Tetrahedron Letters
Volume	36
Issue number	25
DOIs	https://doi.org/10.1016/0040-4039(95)00788-E
State	Published - Jun 19 1995
Externally published	Yes

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/0040-4039(95)00788-E

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title = "Asymmetric reduction of keto oxime ethers using oxazaborolidine reagents. The enantioselective synthesis of cyclic amino alcohols",

abstract = "Asymmetric reduction of keto oxime ethers 2 catalyzed by oxazaborolidine-borane complex 4 produces the cis amino alcohols 1 efficiently and with high levels of diastereo- and enantioselectivity.",

author = "Tillyer, {Richard D.} and Charles Boudreau and David Tschaen and Dolling, {U. H.} and Reider, {Paul J.}",

year = "1995",

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doi = "10.1016/0040-4039(95)00788-E",

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AU - Tillyer, Richard D.

AU - Boudreau, Charles

AU - Tschaen, David

AU - Dolling, U. H.

AU - Reider, Paul J.

PY - 1995/6/19

Y1 - 1995/6/19

N2 - Asymmetric reduction of keto oxime ethers 2 catalyzed by oxazaborolidine-borane complex 4 produces the cis amino alcohols 1 efficiently and with high levels of diastereo- and enantioselectivity.

AB - Asymmetric reduction of keto oxime ethers 2 catalyzed by oxazaborolidine-borane complex 4 produces the cis amino alcohols 1 efficiently and with high levels of diastereo- and enantioselectivity.

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U2 - 10.1016/0040-4039(95)00788-E

DO - 10.1016/0040-4039(95)00788-E

M3 - Article

AN - SCOPUS:0029058104

SN - 0040-4039

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 25

ER -

Asymmetric reduction of keto oxime ethers using oxazaborolidine reagents. The enantioselective synthesis of cyclic amino alcohols

Abstract

All Science Journal Classification (ASJC) codes

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