Abstract
The addition of 2-lithio-2-methylpropionitrile (1) to chirally modified η6-arene-tricarbonylchromium complexes (5) leads to the formation of 2-(cyclohex-2-en-1-on-5-yl)-2-methylpropionitrile (4) in good yields and, under thermodynamically controlled conditions, with up to 48% ee.
Original language | English (US) |
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Pages (from-to) | 3089-3092 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 37 |
Issue number | 18 |
DOIs | |
State | Published - Apr 29 1996 |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Drug Discovery
- Organic Chemistry