Ascidian embryogenesis and the origins of the chordate body plan

Anna Di Gregorio, Michael Steven Levine

Research output: Contribution to journalArticle

58 Scopus citations

Abstract

For more than a century, ascidians have been a widely used system for classic embryological studies. Ascidians possess simple, well-defined cell-lineages, compact genomes, rapid development and world-wide distribution. Transgenic DNA can be introduced into developing embryos using simple electroporation methods. The ascidian larva represents the most simplified chordate body plan and provides a useful model for studying the molecular pathways underlying the morphogenesis and differentiation of the notochord and neural tube.

Original languageEnglish (US)
Pages (from-to)457-463
Number of pages7
JournalCurrent Opinion in Genetics and Development
Volume8
Issue number4
DOIs
StatePublished - Jan 1 1998
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Genetics
  • Developmental Biology

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