Approaching the molecular origins of collective dynamics in oscillating cell populations

Pankaj Mehta, Thomas Gregor

Research output: Contribution to journalReview article

20 Scopus citations

Abstract

From flocking birds, to organ generation, to swarming bacterial colonies, biological systems often exhibit collective behaviors. Here, we review recent advances in our understanding of collective dynamics in cell populations. We argue that understanding population-level oscillations requires examining the system under consideration at three different levels of complexity: at the level of isolated cells, homogenous populations, and spatially structured populations. We discuss the experimental and theoretical challenges this poses and highlight how new experimental techniques, when combined with conceptual tools adapted from physics, may help us overcome these challenges.

Original languageEnglish (US)
Pages (from-to)574-580
Number of pages7
JournalCurrent Opinion in Genetics and Development
Volume20
Issue number6
DOIs
StatePublished - Dec 2010

All Science Journal Classification (ASJC) codes

  • Genetics
  • Developmental Biology

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