Abstract
A rationally designed mechanistic approach to anti-Markovnikov olefin hydrofunctionalization and its application to the synthesis of heterocycles are described. Porphyrin-rhodium complexes have been shown to exhibit remarkable reactivity and selectivity for each step of the proposed catalytic cycle (see scheme). A critical step of this reaction sequence is a new, facile, and remarkably general carbon-heteroatom bond-forming reductive elimination.
Original language | English (US) |
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Pages (from-to) | 588-590 |
Number of pages | 3 |
Journal | Angewandte Chemie - International Edition |
Volume | 43 |
Issue number | 5 |
DOIs | |
State | Published - Jan 23 2004 |
All Science Journal Classification (ASJC) codes
- General Chemistry
- Catalysis
Keywords
- Alkenes
- Hydroamination
- Porphyrinoids
- Reductive elimination
- Rhodium