An improved and practical procedure for the synthesis of substituted phenylacetylpyridines

Michel Journet; Dongwei Cai; Robert D. Larsen; Paul J. Reider

doi:10.1016/S0040-4039(98)00140-3

An improved and practical procedure for the synthesis of substituted phenylacetylpyridines

Michel Journet, Dongwei Cai, Robert D. Larsen, Paul J. Reider

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

A general procedure for the synthesis of substituted phenylacetylpyridines in excellent yields is described using a Horner-Emmons condensation between α-aminoalkylphosphonates of pyridinecarboxaldehydes and benzaldehydes with cesium carbonate at room temperature.

Original language	English (US)
Pages (from-to)	1717-1720
Number of pages	4
Journal	Tetrahedron Letters
Volume	39
Issue number	13
DOIs	https://doi.org/10.1016/S0040-4039(98)00140-3
State	Published - Mar 26 1998
Externally published	Yes

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(98)00140-3

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title = "An improved and practical procedure for the synthesis of substituted phenylacetylpyridines",

abstract = "A general procedure for the synthesis of substituted phenylacetylpyridines in excellent yields is described using a Horner-Emmons condensation between α-aminoalkylphosphonates of pyridinecarboxaldehydes and benzaldehydes with cesium carbonate at room temperature.",

author = "Michel Journet and Dongwei Cai and Larsen, \{Robert D.\} and Reider, \{Paul J.\}",

year = "1998",

month = mar,

day = "26",

doi = "10.1016/S0040-4039(98)00140-3",

language = "English (US)",

volume = "39",

pages = "1717--1720",

journal = "Tetrahedron Letters",

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number = "13",

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T1 - An improved and practical procedure for the synthesis of substituted phenylacetylpyridines

AU - Journet, Michel

AU - Cai, Dongwei

AU - Larsen, Robert D.

AU - Reider, Paul J.

PY - 1998/3/26

Y1 - 1998/3/26

N2 - A general procedure for the synthesis of substituted phenylacetylpyridines in excellent yields is described using a Horner-Emmons condensation between α-aminoalkylphosphonates of pyridinecarboxaldehydes and benzaldehydes with cesium carbonate at room temperature.

AB - A general procedure for the synthesis of substituted phenylacetylpyridines in excellent yields is described using a Horner-Emmons condensation between α-aminoalkylphosphonates of pyridinecarboxaldehydes and benzaldehydes with cesium carbonate at room temperature.

UR - https://www.scopus.com/pages/publications/0032568279

UR - https://www.scopus.com/inward/citedby.url?scp=0032568279&partnerID=8YFLogxK

U2 - 10.1016/S0040-4039(98)00140-3

DO - 10.1016/S0040-4039(98)00140-3

M3 - Article

AN - SCOPUS:0032568279

SN - 0040-4039

VL - 39

SP - 1717

EP - 1720

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 13

ER -

An improved and practical procedure for the synthesis of substituted phenylacetylpyridines

Abstract

All Science Journal Classification (ASJC) codes

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