An improved and practical procedure for the synthesis of substituted phenylacetylpyridines

Michel Journet, Dongwei Cai, Robert D. Larsen, Paul J. Reider

Research output: Contribution to journalArticle

16 Scopus citations

Abstract

A general procedure for the synthesis of substituted phenylacetylpyridines in excellent yields is described using a Horner-Emmons condensation between α-aminoalkylphosphonates of pyridinecarboxaldehydes and benzaldehydes with cesium carbonate at room temperature.

Original languageEnglish (US)
Pages (from-to)1717-1720
Number of pages4
JournalTetrahedron Letters
Volume39
Issue number13
DOIs
StatePublished - Mar 26 1998
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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