TY - JOUR
T1 - Amygdala unit activity during sleep and waking
AU - Jacobs, Barry L.
AU - McGinty, Dennis J.
N1 - Funding Information:
1 Based on a dissertation submitted by the first author in partial requirements for the PhD degree at the University of California, ported by U.S.P.H.S. Grant MH-10083, the Veterans Administration, predoctoral fellowship (1 FOl MH473&01). Th e authors thank R. Harper, and M. Sterman for their assistance in the preparation of Reprint requests should be sent to Barry L. Jacobs, Sleep Laboratory, partment, Stanford University Medical School, Stanford, California
PY - 1971/10
Y1 - 1971/10
N2 - Unit activity was recorded from the basolateral amygdala of freely moving cats during quiet waking (QW), slow-wave sleep (SWS), and paradoxical sleep (PS), and in response to sensory stimuli. Nichrome wires, 65 μ in diameter, implanted in bundles of ten each, served as the microelectrodes. Most cells in this region discharged at very low rates (< 1 spike/sec) during all states; the majority of cells ( 39 61) discharged at significantly higher rates during SWS than in either PS or QW; and no increase in discharge rate was seen in association with the phasic activity of PS. All of these results are contrary to those generally reported for other brain loci. Cells that discharged at their highest rates during SWS represented a distinctly different class of cells than the faster firing cells that discharged fastest in PS or QW. These slowly firing cells exhibited high-rate bursts in PS, increased discharge rates in association with EEG synchrony observed over the sensorimotor cortex during PS, and selective responsiveness to complex sensory stimuli.
AB - Unit activity was recorded from the basolateral amygdala of freely moving cats during quiet waking (QW), slow-wave sleep (SWS), and paradoxical sleep (PS), and in response to sensory stimuli. Nichrome wires, 65 μ in diameter, implanted in bundles of ten each, served as the microelectrodes. Most cells in this region discharged at very low rates (< 1 spike/sec) during all states; the majority of cells ( 39 61) discharged at significantly higher rates during SWS than in either PS or QW; and no increase in discharge rate was seen in association with the phasic activity of PS. All of these results are contrary to those generally reported for other brain loci. Cells that discharged at their highest rates during SWS represented a distinctly different class of cells than the faster firing cells that discharged fastest in PS or QW. These slowly firing cells exhibited high-rate bursts in PS, increased discharge rates in association with EEG synchrony observed over the sensorimotor cortex during PS, and selective responsiveness to complex sensory stimuli.
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U2 - 10.1016/0014-4886(71)90097-5
DO - 10.1016/0014-4886(71)90097-5
M3 - Article
C2 - 5119953
AN - SCOPUS:0015137594
SN - 0014-4886
VL - 33
SP - 1
EP - 15
JO - Experimental Neurology
JF - Experimental Neurology
IS - 1
ER -