Aluminum‒Amine Complexes for the Conversion of Carboxylic Esters to Amides. Application to the Synthesis of LTD4 Antagonist MK-0679

Daniel R. Sidler; Thomas C. Lovelace; James M. McNamara; Paul J. Reider

doi:10.1021/jo00085a001

Aluminum‒Amine Complexes for the Conversion of Carboxylic Esters to Amides. Application to the Synthesis of LTD₄ Antagonist MK-0679

Daniel R. Sidler, Thomas C. Lovelace, James M. McNamara, Paul J. Reider

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Abstract

The preparation and characterization of N,N-dimethylammonium dialkylaluminum chloride and the use of these complexes in the synthesis of the LTD₄ antagonist MK-0679 is described.

Original language	English (US)
Pages (from-to)	1231-1233
Number of pages	3
Journal	Journal of Organic Chemistry
Volume	59
Issue number	6
DOIs	https://doi.org/10.1021/jo00085a001
State	Published - Mar 1 1994
Externally published	Yes

All Science Journal Classification (ASJC) codes

Organic Chemistry

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10.1021/jo00085a001

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title = "Aluminum‒Amine Complexes for the Conversion of Carboxylic Esters to Amides. Application to the Synthesis of LTD4 Antagonist MK-0679",

abstract = "The preparation and characterization of N,N-dimethylammonium dialkylaluminum chloride and the use of these complexes in the synthesis of the LTD4 antagonist MK-0679 is described.",

author = "Sidler, {Daniel R.} and Lovelace, {Thomas C.} and McNamara, {James M.} and Reider, {Paul J.}",

year = "1994",

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doi = "10.1021/jo00085a001",

language = "English (US)",

volume = "59",

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journal = "Journal of Organic Chemistry",

issn = "0022-3263",

publisher = "American Chemical Society",

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T1 - Aluminum‒Amine Complexes for the Conversion of Carboxylic Esters to Amides. Application to the Synthesis of LTD4 Antagonist MK-0679

AU - Sidler, Daniel R.

AU - Lovelace, Thomas C.

AU - McNamara, James M.

AU - Reider, Paul J.

PY - 1994/3/1

Y1 - 1994/3/1

N2 - The preparation and characterization of N,N-dimethylammonium dialkylaluminum chloride and the use of these complexes in the synthesis of the LTD4 antagonist MK-0679 is described.

AB - The preparation and characterization of N,N-dimethylammonium dialkylaluminum chloride and the use of these complexes in the synthesis of the LTD4 antagonist MK-0679 is described.

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U2 - 10.1021/jo00085a001

DO - 10.1021/jo00085a001

M3 - Article

AN - SCOPUS:0028295615

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JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

IS - 6

ER -

Aluminum‒Amine Complexes for the Conversion of Carboxylic Esters to Amides. Application to the Synthesis of LTD₄ Antagonist MK-0679

Abstract

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