Alternative Splicing: Regulation of Drosophila melanogaster Sex Determination

J. K.M. Penn; P. Graham; P. Schedl; H. K. Salz

doi:10.1016/B978-0-12-378630-2.00316-9

Alternative Splicing: Regulation of Drosophila melanogaster Sex Determination

J. K.M. Penn, P. Graham, P. Schedl, H. K. Salz

Molecular Biology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Alternative splicing of pre-mRNAs is widespread in eukaryotes and provides a key mechanism for generating different gene products, often with distinct or specialized functions, from a single transcription unit. In insects, alternative splicing plays an especially important role in the process of sex determination, providing the mechanism for remembering sexual identity (determination) and for orchestrating sexual development (differentiation).

Original language	English (US)
Title of host publication	Encyclopedia of Biological Chemistry
Subtitle of host publication	Second Edition
Publisher	Elsevier Inc.
Pages	81-86
Number of pages	6
ISBN (Electronic)	9780123786319
ISBN (Print)	9780123786302
DOIs	https://doi.org/10.1016/B978-0-12-378630-2.00316-9
State	Published - Feb 15 2013

All Science Journal Classification (ASJC) codes

General Biochemistry, Genetics and Molecular Biology

Keywords

Alternative splicing
Blockage mechanism
Doublesex
Fruitless
SR proteins
Sex determination
Sex lethal
Splice site activation
Spliceosome complexes
Splicing
Transformer

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10.1016/B978-0-12-378630-2.00316-9

Cite this

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abstract = "Alternative splicing of pre-mRNAs is widespread in eukaryotes and provides a key mechanism for generating different gene products, often with distinct or specialized functions, from a single transcription unit. In insects, alternative splicing plays an especially important role in the process of sex determination, providing the mechanism for remembering sexual identity (determination) and for orchestrating sexual development (differentiation).",

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T2 - Regulation of Drosophila melanogaster Sex Determination

AU - Penn, J. K.M.

AU - Graham, P.

AU - Schedl, P.

AU - Salz, H. K.

PY - 2013/2/15

Y1 - 2013/2/15

N2 - Alternative splicing of pre-mRNAs is widespread in eukaryotes and provides a key mechanism for generating different gene products, often with distinct or specialized functions, from a single transcription unit. In insects, alternative splicing plays an especially important role in the process of sex determination, providing the mechanism for remembering sexual identity (determination) and for orchestrating sexual development (differentiation).

AB - Alternative splicing of pre-mRNAs is widespread in eukaryotes and provides a key mechanism for generating different gene products, often with distinct or specialized functions, from a single transcription unit. In insects, alternative splicing plays an especially important role in the process of sex determination, providing the mechanism for remembering sexual identity (determination) and for orchestrating sexual development (differentiation).

KW - Alternative splicing

KW - Blockage mechanism

KW - Doublesex

KW - Fruitless

KW - SR proteins

KW - Sex determination

KW - Sex lethal

KW - Splice site activation

KW - Spliceosome complexes

KW - Splicing

KW - Transformer

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SN - 9780123786302

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EP - 86

BT - Encyclopedia of Biological Chemistry

PB - Elsevier Inc.

ER -

Alternative Splicing: Regulation of Drosophila melanogaster Sex Determination

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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